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Other small studies have demonstrated benefits from the drug for patients with diastolic heart failure who also had high blood pressure, right ventricular dysfunction and pulmonary arterial hypertension. Whats driving the high rates of type 2 diabetes is the obesity epidemic�theres no question about this. Today we launch a four-week series on type 2 diabetes by talking to Dr. Zinman. Nutrient excess, obesity and a sedentary life style are the principal causes of diabetes. There is no specific food type that causes diabetes, but refined sugars and fat are major sources of the nutrient excess. But the researchers discovered that these improvements occurred largely because some people achieve major gains with sildenafil at altitude while others improve much less or not at all. 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